# Example 32 — Nonparametric Support Points **Script:** `examples/32_nonparametric_support_points.py` This example demonstrates nonparametric population estimation on a synthetic one-compartment oral PK dataset with a single ETA on clearance. The synthetic dataset keeps runtime short while still producing a non-degenerate support-point distribution. ## What it shows - `NONPARAMETRIC` estimation with a deterministic synthetic dataset. - A support-point approximation to the empirical ETA distribution. - The highest-weight support points and empirical ETA moments. ## Model The example uses: - ADVAN2 / TRANS2 - fixed structural parameters `KA` and `V` - one random effect on `CL` - proportional residual error This narrower setup is deliberate: it is much easier to obtain an informative, fast support-point example with one ETA than with a heavier multi-ETA real-data workflow. ## Notes - The printed `converged` flag comes from the base parametric fit used to seed the support points. The support-point distribution itself is the important artifact in this example. - The example is intended as a runnable illustration, not an external scientific reference dataset.